CRISPR - The right technology for the "cure"


CRISPR - Clustered Regulatory Interspaced Short Palindromic Repeats, a family of the DNA sequence in bacteria contains snippets of DNA which are used by the bacterium to detect and destroy the DNA of viruses which is considered as a defense system for the bacteria .This has been used as a effective tool for changing the genes within the organisms.

In the treatment of AIDS, DNA of the HIV is inserted into the genome of the host where it can lay dormant for years and its effects can be changed slightly as the virus cannot be made to remain in the inactive state permanently. In the recent days, scientists proved that it is possible to cut the HIV cells out of living cells of patients in a laboratory using CRISPR. Currently, they carried out an experiment in the lab with the rats which had HIV in 99 per cent of their cells. By injecting CRISPR into the rat’s tails, they were able to remove 48 per cent of the virus from the DNA of their body cells. Although the experiments are done in the early stage, it is ascertain that CRISPR proves to be the ultimate tool for the treatment of AIDS. CRISPR/CAS9 could also mean a revolution for the pharmaceutical industry where new types of drugs are developed for the chronic diseases which were previously considered to be incurable. At present, CRISPR-based drugs  are developed to treat heart disease, blood disorders, and blindness and the manufacturing of drug is focused mainly on the genetic methods.

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